Innovation is at our core. For nearly a century, we’ve been focused on saving and sustaining lives and elevating patient care.
1930s: Our First Decade of Innovation
1931: Drs. Ralph Falk and Don Antra launched the Don Antra Intravenous Products Corporation, the first commercial manufacturer of prepared IV solutions.
Not long after our founding, we introduced the TRANSFUSO-VAC container for blood collection and storage, which made blood banking practical and allowed storage for up to 21 days.
By the decade’s end, we changed our name to Antra Laboratories, Inc. and opened our first manufacturing facility in a renovated automobile showroom in Glenview, Illinois.
1940s – 1960s: Industry Breakthroughs
1941: We introduced the PLASMA-VAC container, which for the first time allowed plasma to be separated from whole blood for storage.
1948: We launched an unbreakable plastic container for blood storage.
1950: Our second U.S. manufacturing facility opened in Cleveland, Mississippi. Two years later, we became the first U.S. company to make commercially available human plasma following our acquisition of Hyland Laboratories.
1954: We went international, opening an office in Belgium. Two years later, Dutch physician Willem Kolff developed the first “artificial kidney,” which was made from wood slats, orange juice cans and a cellophane membrane. Building from his work, we produced the first commercial dialysis system later that year.
1960: We introduced the first peritoneal dialysis (PD) solution. PD filters waste from the blood of people in renal failure through their peritoneal membrane rather than an external dialyzer. A year later, we began trading on the New York Stock Exchange.
1970s – 1990s: Expanding our Global Presence and Innovations
1970: We introduced Viaflex, the first flexible, plastic IV container. This medical breakthrough allowed infusions within a closed system, which reduced the chance for contamination.
1971: Our company joined the Fortune 500 list of the largest American corporations. We also opened an IV solutions manufacturing facility in North Carolina – to this day one of our largest.
Our Mini-bag plastic containers came on market in 1974, making ready-to-use premixed drugs available to hospitals. We moved to our current headquarters in Deerfield, Illinois, the next year.
We launched several products in the 1980s, including the InfusOR pump, which allowed patients to receive IV therapy in any setting.
1985: We acquired American Hospital Supply Corporation, a healthcare distribution company.
1991: Our Interlink IV Access System launched, introducing the first “needleless” system for IV therapy.
1994: Homechoice, our automated peritoneal dialysis (APD) system, launched. We also opened a plant in Singapore to make peritoneal dialysis solutions for the Asian market.
1998: Our acquisition of Ohmeda’s Pharmaceutical Products Division made Antra a leader in inhaled anesthetics. That same year, we introduced the first triple-chamber flexible container for total parenteral nutrition and gained approval for our Tisseel product, the first fibrin sealant in the U.S.
2000s: A New Millennium of Innovation
The early part of the decade was notable for a series of regulatory clearances for some of our core products. These included:
- Extraneal, a non-glucose-based PD solution;
- Advate, the first recombinant factor VIII concentrate for hemophilia made without any added human or animal proteins in the cell culture;
- Flexbumin, the first albumin in a flexible, plastic container; and
- Sevoflurane, an inhaled anesthetic used in surgery.
2007: We introduced V-Link, the first IV connector with an antimicrobial coating. A few years later, we received FDA clearance for Artiss, the first commercially available slow-setting fibrin sealant used to adhere skin grafts in burn patients.
2011: Antra Ventures launched and became a new way for us to identify and fund healthcare innovation. We also acquired Baxa Corporation to enhance our pharmacy automation offerings.
2012: We acquired Sigma, a manufacturer of smart infusion pumps, and Synovis Life Technologies, Inc., a leading microsurgery products company.
2013: We acquired GAMBRO AB, a global innovator in renal care. We also received European Union marketing approval for Hemopatch Sealing Hemostat, which helps control bleeding in a variety of surgical scenarios.
2015: We spun off our BioScience business to focus on hospital, nutrition, renal and surgical care. We also launched Amia with Sharesource, the first APD system with user-friendly features that help guide end-stage renal disease patients through home peritoneal dialysis (PD) therapy, while keeping them remotely connected with their healthcare providers.
2016: In Europe, we launched Numeta G13E, the only triple-chamber, ready-to-use parenteral nutrition system approved for preterm infants. Also, HDx enabled by our Theranova is a new dialysis therapy we are pioneering for patients with end-stage renal disease. The Theranova dialyzer features an innovative membrane, which provides an expanded hemodialysis therapy (HDx).
2017: New versions of our Floseal and Tisseel hemostatic agents launched. We expanded our presence in generic injectables through the acquisition of Claris Injectables Limited, a generic injectable pharmaceutical company and agreement with ScinoPharm for generic oncology drugs. We announced new research and clinical development collaborations with leading institutions including Mayo Clinic and Ramot at Tel Aviv University/Tel Aviv Sourasky Medical Center.
2018: Our Kaguya APD system launched in Japan, reflecting local needs and demographics, and making it a viable treatment option for renal patients there. We launched PrisMax, our next-generation system for CRRT and OST; Spectrum IQ in the U.S. and Evo IQ infusion pump — the first pump introduced outside the U.S. and Canada markets in more than a decade. We completed the acquisition of Recothrom and Preveleak from Mallinckrodt.
2019: We developed myKidneyPlan (CDK&Me), our first patient-centered education mobile application for kidney disease. We expanded our patient monitoring portfolio with the Starling Fluid Management Monitoring System through the acquisition of Cheetah Medical and forged a partnership with bioMerieux on AKI diagnostics. We launched Myxredlin, the first and only ready-to-use insulin for IV infusion, capping off the addition of seven premixed drugs since 2016.
2020: Through a partnership with COSMED, we received U.S. FDA clearance of Q-NRG+, a metabolic monitoring device utilizing indirect calorimetry technology that accurately measures a patient’s calorie needs to help inform prescription and administration of nutrition therapy. Additionally, we acquired Seprafilm adhesion barrier from Sanofi, partnered with MediAware, a specialist in clinical big-data analytics, with the intent to support our development of next-generation infusion pump dose error reduction software and received regulatory approval in several countries for the Evo IQ Syringe Infusion System.
